- Product Details
Keywords
- Sorafenib
- SORAFENIB-D3
- SORAFENIB TOLSYLATE
Quick Details
- ProName: Sorafenib
- CasNo: 284461-73-0
- Molecular Formula: 284461-73-0
- Application: Anti-cancer
- PackAge: 25kg/drum
- Port: shanghai
- ProductionCapacity: Metric Ton/Day
- Purity: 99%
- Transportation: by sea/by air
- LimitNum: 0 Metric Ton
Superiority
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Details
Product Name: | Sorafenib tosylate |
Synonyms: | sorafenib;SORAFENIB-D3;SORAFENIB TOLSYLATE;RAF1 KINASE INHIBITOR II;N-(4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)-((4-(2-(N-METHYL-CARBAMOYL)(4-PYRIDYLOXY))PHENYL)AMINO)CARBOXAMIDE;4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-n-methyl-pyridine-2-carboxamide;BAY 43-9006;SORAFENIB MESYLATE |
CAS: | 284461-73-0 |
MF: | C21H16ClF3N4O3 |
MW: | 464.83 |
EINECS: | |
Product Categories: | Sorafinib;Molecular Targeted Antineoplastic;All Inhibitors;anti-neoplastic;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate;Amines;Inhibitor;Bay 43-9006 |
Mol File: | 284461-73-0.mol |
Sorafenib tosylate Chemical Properties |
mp | 202-204°C |
storage temp. | -20°C Freezer |
CAS DataBase Reference | 284461-73-0(CAS DataBase Reference) |
Safety Information |
Sorafenib tosylate Usage And Synthesis |
Chemical Properties | Light Yellow Solid |
Usage | A potent RAF kinase inhibitor. Antineoplastic |
Usage | Multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic. |
Usage | Sorafenib Tosylate (Bay 43-9006, Nexavar) is a small molecular inhibitor of VEGFR, PDGFR, c-Raf and B-Raf with IC50s of 18 nM, 10 nM, 3 nM and 15 nM, respectively. |
Usage | Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively - See more at: # |